Skip to content
Open access

Impact of premature mortality attributable to obesity on years of life lost in Brazil

Oct 2025 · medRxiv · Vol 70 · 0 citations · 25 references
Medicine

TL;DR

An increasing trend in premature mortality due to obesity in Brazil is highlighted, disproportionately affecting older populations, particularly women, and the need for targeted public health interventions to mitigate obesity-related years of life lost is highlighted.

Abstract

Background: Obesity represents a substantial global health burden, and obesity driven premature mortality remains a persistent public health challenge. Although the association between obesity and reduced lifespan is well established, a precise quantification of the estimated years of life lost (YLL) directly attributable to obesity remains a notable gap in research. Objective: To quantify the societal burden of obesity in Brazil by estimating YLL due to premature mortality between 2014 and 2023. Methods: Life expectancy in Brazil is 76.4 years; thus, premature death was defined as occurring before age 60. This study employed a quantitative epidemiological approach to estimate YLL due to obesity in Brazil (2014/2023). Mortality data were obtained from the Mortality Information System, and demographic projections were sourced from IBGE. YLL was calculated by multiplying deaths by remaining life expectancy (using GBD 2021 reference tables), stratified by age and sex. Statistical analysis was performed using PSPP, and visualizations were generated using Python, with results presented as rates per 100,000 population. Results: The total number of events exhibited an increasing trend over the decade, with a notable peak post 2020, coinciding with the COVID19 pandemic. The age groups 50/59 and 60/69 consistently showed the highest event frequency, indicating greater prevalence among older populations. Sex specific analysis revealed variations across age groups and years. While events were rare in younger age categories (1/14), a marked increase was observed from age 15/19 onward. Notably, in older age groups (40/69), females exhibited higher event rates than males, particularly in the 60/69 bracket, suggesting a sex-based disparity in obesity/related mortality. Conclusion: This study highlights an increasing trend in premature mortality due to obesity in Brazil, disproportionately affecting older populations, particularly women. The observed age and sex disparities underscore the need for targeted public health interventions to mitigate obesity-related years of life lost. Keywords: Obesity, Years of Life Lost, Premature Mortality.

Read PDF

Similar papers

Open access Mar 2026

The Hidden Burden: Global, Regional, and National Trends in Indirect Cause of Maternal Mortality from 1980 to 2021: A Global Analysis Using the Global Burden of Disease 2021 Data

Introduction: Worldwide, lowering maternal mortality is a top priority. While significant efforts have been made to address direct obstetric complications, indirect causes such as pre-existing medical conditions that are aggravated by pregnancy remain a major cause of mortality but are often unrecognized. Understanding...

Abebaw Alamrew, Chalie Mulugeta, Ayinalem Yetwale et al. · 0 citations
Aug 2026

The rising disabling share of health loss among adults aged 80 years and older: A 34-year GBD 2023 analysis across 10 selected countries, 1990-2023.

BACKGROUND Increasing life expectancy has created an epidemiological paradox of declining mortality alongside sustained disability, particularly among the oldest-old. We quantified changes in the fatal and non-fatal composition of health loss among adults aged ≥80 years in 10 selected countries. METHODS We analyzed G...

Jia-Ying Wu, Zhen Zheng, Jia-Ming Wu · 0 citations
Sep 2026

Global Burden of Pediatric Stroke (1990-2023): A Shift From Mortality Toward Disability.

BACKGROUND Pediatric stroke is a significant cause of long-term disability worldwide, with outcomes influenced by age, stroke subtype, and access to care. Our objective was to define the global burden of pediatric stroke by its impact on mortality and disability. METHODS The Global Burden of Disease study uses advanc...

C. Rawson, Lisa M. Pabst, Karol P. Budohoski et al. · 0 citations
Open access Sep 2026

The Burden of Disease Attributable to Diet Low in Vegetables From 1990 to 2021: A Global Analysis

ABSTRACT The global epidemiological landscape of diseases attributable to diet low in vegetables remains insufficiently characterized. This study aims to provide a comprehensive assessment of the disease burden associated with this risk on a global scale. Using data from the Global Burden of Diseases, Injuries, and Ris...

Xin-Di Wei, Xiao-Meng Zhang, Xiao-Lei Lv et al. · 0 citations
Open access 2026

Time Trends in Mortality from Cardiovascular Diseases: An Ecological Study of Brazil's Regions and States, 2010-2023.

BACKGROUND Death from cardiovascular diseases (CVD) represents an essential marker for evaluating the progress and limitations of public policies, especially in territories with greater vulnerability. OBJECTIVE To analyze mortality from CVD, hypertensive diseases (HD), ischemic heart disease (IHD), and cerebrovascula...

José Francisco Kerr Saraiva, A. C. Campos, Gisele O'Dwyer et al. · 0 citations
Open access Oct 2026

Trends in mortality involving chronic obstructive pulmonary disease and obesity in the United States, 1999–2023

Chronic obstructive pulmonary disease (COPD) and obesity are major US public health conditions that frequently coexist. Despite adverse respiratory and cardiometabolic effects of obesity, an apparent “obesity paradox,” whereby obesity has been associated with lower mortality in some patients with COPD, has been describ...

AM Khan, Syed Azfar Hussain, Z. Ahmad et al. · 0 citations

We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.