Results in this project indicate that SP1561 might be essential to S. pneumoniae and cannot be knocked out, and results from attempts to create knock out mutants for SP1561 are presented.
Streptococcus anginosus is an opportunistic pathogen causing bacteremia, respiratory tract infections, abscesses, odontogenic infections and has recently been associated with gastric cancer. While numerous genes encoding putative virulence factors have been detected in whole genome sequences, a detailed molecular chara...
Simon Jooß, Verena Vogel, Richard J. Bauer et al.· bioRxiv· 0 citations
These results suggested the presence of an alternate bL27-processing protease in TIGR4 that was absent from D39, and shed light on an alternative mechanism for bL27 maturation, and indicate that some strains of S. pneumoniae harbor horizontally acquired redundant pathways for this essential ribosome processing step.
Amarshi Mukherjee, Mohamed O. Nasef, Patrick M. Lindstrom et al.· bioRxiv· 0 citations
Klebsiella pneumoniae has emerged as a significant pathogen globally, particularly in clinical settings, resulting in severe infections, including UTI, respiratory tract infections, and bloodstream infections, and the high rates of resistance to the most common drugs make it very difficult to treat. Numerous characteri...
Hawraa Qasim Owaid, Maysoom Kh Abbas· Journal of the College of B...· 0 citations
Background:
Zoonotic diseases are illnesses that humans can contract from animals and vice versa. Pseudomonas aeruginosa is an opportunistic organism that makes treating infections challenging, particularly in individuals with underlying medical conditions and those with impaired immune systems. The increasing number o...
Abdul-Nafea Hassan, Ibtisam Q. Abdulkareem· Open Veterinary Journal· 0 citations
Simple Summary Tuberculosis, caused by the bacterium Mycobacterium tuberculosis, remains one of the world’s deadliest infectious diseases. Identifying which bacterial genes aid survival and transmission could reveal new therapeutic targets. In this study, we studied Rv3787c, which belongs to a family of genes encoding...
M. M. Bigi, R. Rocha, E. García et al.· Biology· 0 citations
An RNase-encoding gene is identified that is present in methicillin-susceptible strains, but absent from resistant counterparts, and acts as a barrier to the uptake of mobile genetic elements in Staphylococcus aureus.
Kohei Kondo, A. Azam, J. Hisatsune et al.· Nature Communications· 0 citations
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