TL;DR
The significant differences in plasma levels of ferroptosis-related biomarkers between RRMS patients and healthy controls suggest a potential role for ferroptosis in the pathogenesis of multiple sclerosis.
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease in which oxidative stress and inflammation are closely linked, yet integrated evaluation of these processes in Iraqi patients remains limited. This cross-sectional case-control study included 80 adults in Baghdad, Iraq: 40 patients fulfilling the 2010 A...
INTRODUCTION Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid-lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non-drug treatment using double-filtration plas...
Initiation of DMTs in RRMS patients was associated with a significant decrease in sNfL levels, suggesting reduced neuroaxonal damage following treatment introduction, and monitoring sNfL may represent a useful non-invasive biomarker of biological treatment response in RRMS patients.
IFNG‐AS1 demonstrates promising diagnostic potential for MS, whereas UCHL1‐AS1 shows only modest discriminatory value, however, these findings are preliminary and require further validation with functional studies to confirm clinical utility.
Chronic spontaneous urticaria (CSU) is monitored mainly with patient-reported outcomes, whereas objective biomarkers that reflect disease status remain limited. This prospective observational cohort study included 55 adults with antihistamine-refractory CSU who initiated omalizumab as part of routine clinical care and...
Introduction: Multiple sclerosis (MS) is an demiyelinating autoimmune disease and characterized with chronic inflammation and neurodegeneration. Resistin is an adipokine secreted from adipose tissue and known to be a pro-inflammatory mediator produced mainly by monocytes and macrophages in humans, has an uncertain role...
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