Evaluation of a Sol-Gel Zirconia-Silver Coating for Titanium Implants: Assessing Biocompatibility, Osseointegration, and Enhanced Short-Term Antibacterial Efficacy.
Sep 2026· Annals of Biomedical Engineering· 1 citation· 45 references
Medicine
TL;DR
Findings indicate that Solgel_Ti represents a promising dual-functional surface modification strategy that successfully combines antibacterial activity with preserved osseointegration and offers a viable pathway for the development of safe, infection-resistant orthopedic implants with long-term clinical potential.
Orthopedic site infections remain a growing concern in implantology, particularly in light of rising antibiotic resistance. Identifying optimal, standardized antimicrobial treatments is increasingly challenging. Beyond the design and functional properties of orthopedic materials, key factors such as bacterial adhesion...
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The long-term success of orthopedic implants depends not only on their mechanical performance but also on their ability to establish a stable and biologically active interface with surrounding tissues. Despite the widespread clinical use of metallic, ceramic, and polymeric biomaterials, implant failure remains associat...
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Spinal surgery involves highly complex procedures where the risk of severe complications, including postoperative infections, may compromise both surgical success and patient survival. In this study, functional coatings for spinal screws were developed to promote bone integration and simultaneously prevent infection. T...
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Additive manufacturing (AM) has emerged as a transformative route for fabricating porous titanium scaffolds with patient-specific geometries and bone-mimicking mechanical responses. By controlling unit-cell architecture, porosity, and surface topography, AM-fabricated Ti and Ti-6Al-4V scaffolds can simultaneously addre...
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Porous orthopedic implants are widely studied because they promote osseointegration and reduce stress shielding associated with dense, stiff implants. This review critically examines recent progress in the design and fabrication of additively manufactured porous orthopedic implants, with a focused emphasis on polylacti...
A. Shehzad, Yan'en Wang, Ghulam Hassan Askari et al.· Biomedical engineering and p...· 0 citations
Developing bioactive and antibacterial composites to address clinical challenges such as bacterial infection and mechanical loosening for titanium-based implants remains a significant challenge at present. In this research, sodium alginate (SA) gel coatings incorporated with varying concentrations of silver nanoparticl...
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