TL;DR
In vivo findings revealed accelerated wound closure, enhanced epidermal regeneration, and modulation of PDGFA, VEGFC, COL1A1, TIMP1, and MMP9 expression, and potential relevance to infection‑associated wound environments.
Severe burn injuries are often associated with excessive and prolonged inflammation, resulting in delayed wound healing and poor tissue regeneration. Accordingly, the development of effective skin substitutes capable of modulating inflammation and promoting tissue repair remains a critical challenge in regenerative med...
A combined therapeutic platform that merges immediate photothermal antibacterial action with sustained pro-healing microenvironment support is presented, offering a promising non-antibiotic solution for infected wound management.
Findings demonstrate that Aloe vera-mediated AgNPs can impart antibacterial functionality to electrospun PVA wound dressings, and careful optimization of the AgNPs concentration is essential to achieve an appropriate balance among antibacterial performance, cytocompatibility, and mechanical properties.
A novel integration of capsaicin-mediated silver nanoparticles within a chitosan–alginate biopolymeric matrix is introduced, providing a multifunctional strategy that enhances both antimicrobial efficacy and wound regeneration compared to conventional systems.
Despite advancements in wound dressing development, effective wound repair still remains an unmet clinical need, as current clinical dressings fail to fully replicate the properties of healthy skin. In this regard, the current study utilizes polycaprolactone (PCL) and silk fibroin (SF) to create wound dressings through...
OBJECTIVE This study aims to develop a novel biogenic nano-formulation of copper oxide nanoparticles (CuO-NPs) using the Moroccan medicinal plant Inula viscosa to address critical challenges in wound care, specifically infection risks and coagulation disorders. SIGNIFICANCE By utilizing bioactive plant compounds as n...
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