TL;DR
Findings support the idea that sleep disturbance provokes epilepsy in susceptible through inflammatory pathways, and suggest that inflammatory processes can play an important role in epileptogenesis in several ways like pro-inflammatory pathways.
Sleep restriction is associated with neuroinflammation, blood-brain barrier (BBB) dysfunction, and cognitive impairment. Although reduced sleep duration in women is well recognized and the impact of sleep disorders is correlated with a higher incidence of neurodegenerative diseases, its consequences during female aging...
Poor sleep quality and chronic psychosocial stress are interrelated risk factors for hypertension, metabolic disease, and neuropsychiatric disorders. Sleep apnea (SA) is a respiratory disorder that disrupts sleep, affecting ~1 billion adults worldwide. However, the origins of SA remain incompletely understood. Clinical...
Extreme cold exposure has emerged as a significant global public health challenge to cognitive function among populations such as military personnel, polar workers, and residents of high-latitude regions. However, the complex mechanisms underlying cold environment-induced cognitive impairment remain to be systematicall...
Sleep is a complex and essential biological process that plays a fundamental role in maintaining physical and mental health. This paper provides a comprehensive overview of the physiological mechanisms underlying sleep, including circadian rhythms, sleep homeostasis, sleep stages, neural regulation, and sleep disorders...
The locus coeruleus (LC) has a major role in mechanisms of arousal, attention, and emotional responses. Increasing evidence indicates that the LC also regulates sleep architecture and triggers phasic autonomic and hemodynamic events during non-rapid eye movement (NREM) sleep. Ultraslow oscillations of LC activity reduc...
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