Deciphering the structural–functional dynamics of glucosyltransferases from novel Apilactobacillus isolates through in silico analysis

Genomic-Based Prediction of Exopolysaccharide Composition and Structure: Insights from Rhizobium and Sinorhizobium Species

A computational approach to predict how beneficial soil bacteria produce natural exopolysaccharides that help them survive and interact with plants is developed, providing a scalable, genome-based method for predicting EPS biosynthetic potential in Rhizobiaceae and usable in other microbial genera.

Comparative genomics reveals hidden biosynthetic diversity in Streptomyces spp. and metal-dependent regulatory features associated with untapped specialized metabolites

The effectiveness of integrated genome-mining strategies for prioritizing cryptic biosynthetic gene clusters is demonstrated and the remarkable biosynthetic potential of newly identified Streptomyces isolates as a source of novel natural products is highlighted.

Identification of cellular intermediates unveils unique enzymes for flagellar glycan biosynthesis in Clostridioides difficile.

This study chemically synthesized two hitherto undescribed biosynthetic intermediates that were predicted based on bioinformatic analyses, CDP-threonine and CDP-N-methylthreonine, and showed that they are involved in the Type A PGM biosynthesis, as evidenced by mass spectrometric analyses of extracts of a set of C. dif...

Whole-Genome Sequence Dataset of Rhodococcus qingshengii IEGM 267—Terpenoid Biotransformer Toward Genetic Functional Annotation

The results of bioinformatics analysis suggest an alternative enzymatic basis for this transformation and provide a foundation for future functional characterization of Rhodococcus qingshengii IEGM 267.

Identification of Novel Polysaccharide from Myxococcus xanthus and its Function in Developmental Sporulation

Bioinformatics analysis of extracellular glycosyl hydrolases mined from the genome of Halophilic Meridianimaribacter sp. CL38.

Insights are provided into putative glycosyl hydrolase candidates for efficient lignocellulosic waste pre-treatment and significant predicted halophilic and thermostable properties are revealed, suggesting these putative enzymes may endure industrial conditions.