CCT2 Promotes Immune Escape in Colorectal Cancer by Regulating the JAK1‐STAT3‐PD‐L1 Axis

Abstract

Colorectal cancer (CRC) is a major global health burden. While immune checkpoint inhibitors have greatly advanced cancer therapy, their therapeutic effects are unsatisfactory in microsatellite‐stable/proficient mismatch repair CRC. This study explored the molecular mechanisms underlying CRC immune evasion.