Sep 2026· GLOBAL JOURNAL OF PHARMACEUTICAL AND SCIENTIFIC RESEARCH· 0 citations
TL;DR
The study concludes that a robust pharmacovigilance framework significantly contributes to safer therapeutic practices and improved patient outcomes.
Abstract
Pharmacovigilance plays a pivotal role in ensuring the safety and efficacy of medicines throughout their lifecycle. With the increasing complexity of drug therapy, polypharmacy, and global drug distribution, monitoring adverse drug reactions (ADRs) has become a critical public health responsibility. This project explores pharmacovigilance as a systematic framework designed to detect, assess, understand, and prevent adverse effects or any other drug-related problems. Through an extensive review of published review articles and regulatory documents, this study synthesizes existing evidence on pharmacovigilance systems, reporting mechanisms, signal detection methodologies, and regulatory practices. Key challenges such as underreporting, lack of awareness among healthcare professionals, and limitations of spontaneous reporting systems are highlighted. The findings emphasize the need for strengthened pharmacovigilance infrastructure, improved reporting culture, and integration of advanced data analytics. The study concludes that a robust pharmacovigilance framework significantly contributes to safer therapeutic practices and improved patient outcomes.
Pharmacovigilance is an essential scientific and regulatory discipline concerned with the detection, assessment, understanding and prevention of adverse drug reactions and other medicine-related problems throughout the life cycle of medicinal products. As pre-marketing clinical trials involve limited and selected popul...
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Sanja Lazarova· INTERNATIONAL CONGRESS FROM...· 0 citations
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