A general overview of the chemotactic cytokines/chemokines that neutrophils can potentially produce, either under inflammatory/immune reactions or during their activation in more prolonged processes, such as in tumors.
This review delineates how bacterial pathogens both induce excessive NET formation, driving endothelial dysfunction, and evade NET-mediated antimicrobial defense and critically examines the signaling crosstalk between the NET formation with other cell death pathways, particularly focusing on the ROS-mediated PAD4-RIPK...
Shwetha Susan Thomas, Geetha B. Kumar, Bipin G. Nair et al.· Frontiers in Immunology· 0 citations
Introduction Neutrophil granulocytes (PMNs) play a crucial role in initial pathogen defense, in part through the release of neutrophil extracellular traps (NETs). These web-like structures are essential for pathogen clearance and preventing dissemination but can also elicit excessive inflammation resulting in tissue da...
S. Bauch, Jan Stoll, B. Lieubeau et al.· Journal of Inflammation Rese...· 0 citations
It is reported that hemolysate modulates NET formation, depending on the inducing agent, and that hemolysis diminishes Gram-negative bacteria-induced neutrophil activation and NET release.
Daniel Gucwa, Anna Such, Elzbieta Kolaczkowska· Frontiers in Immunology· 0 citations
This review brings together current evidence on basophils formation, composition, antimicrobial effects, and possible involvement in inflammatory skin disorders, parasite-related inflammation, and cancer and identifies major knowledge gaps.
Bojan Stojanović, Ivana Milivojcevic Bevc, Milica Dimitrijevic Stojanovic et al.· Cancers· 0 citations
Fungal infections cause substantial morbidity and mortality, particularly in immunocompromised individuals, yet the immune mechanisms that distinguish protective inflammation from tissue-damaging responses remain incompletely understood. Monocyte chemoattractant protein-1, also known as C-C motif chemokine ligand 2 (MC...
Xin-Yi Shi, Erin E. McClelland· Journal of Fungi· 0 citations
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