An automated assay platform that robustly quantifies antibodies against up to 100 antigens in a single reaction, using Luminex suspension array technology, alongside generating ample quality control measures is described.
Extractable nuclear antigen (ENA) antibody testing is universal to the diagnosis of systemic autoimmune rheumatic diseases (SARDs). However, current commercial multiplex platforms require expensive instruments and are often cost-prohibitive for routine testing in low- and middle-income settings. Pictor PictHealth® Immu...
Jung-Hyun Rho, Andrea Kinga, B. Shetty et al.· JIM - Journal of Immunologic...· 0 citations
Chimeric antigen receptor T-cell (CAR-T) therapy has revolutionized the treatment of refractory B-cell malignancies, yet severe cytokine release syndrome (CRS) and unpredictable long-term outcomes remain major clinical challenges. Here, we developed a rapid, scalable, 96-well plate-based strategy for the high-throughpu...
Keyuan Pu, Wanying He, Jiayi Feng et al.· Chemical Science· 0 citations
A rapid, proof-of-concept microfluidic assay for cancer biomarker quantification and functional therapy evaluation that requires only 5 µL of sample, eliminates tedious sample manipulation, and uses commercial antibodies to track both biomarker concentration and functional activity.
Shaked Doron, Lev Brio, Matan Krasner et al.· Biosensors· 0 citations
The multiplex‐bead immunoassay is characterized by its ability to detect multiple analytes simultaneously within a short timeframe and with high precision. Consequently, it is an appealing tool for identifying humoral immune responses to various targets, particularly respiratory viral infections that pose a significant...
Tarfa A. Altorki, M. Basabrain, Abdulaziz Kulthum et al.· Journal of Immunological Res...· 0 citations
Meningitis and encephalitis necessitate rapid pathogen identification to guide therapy, as conventional methods are time-consuming. This study evaluated both the wet-lab analytical performance and the clinical performance evaluation of the Bioeksen Meningitis/Encephalitis Panel (BS-MEP) integrated onto the fully automa...
Mesut Yilmaz, N. Mahroum· Microorganisms· 0 citations
Lateral flow assays (LFAs) have become the foundation of point‐of‐care (POC) diagnostics, valued for their user‐friendly format, cost‐effectiveness, and rapid turnaround time. However, despite their widespread success, most notably in pregnancy testing and infectious disease monitoring, conventional colourimetric LFA...
Aylar Eslami Saed, J. Giaretta, S. Farajikhah et al.· Visual Information Expert Wo...· 0 citations
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