Association between ePWV and delirium risk in icu sepsis patients: a retrospective analysis based on the MIMIC database and development of a predictive model

Abstract

Highlights • ePWV is an independent predictor of delirium in ICU sepsis patients.• Nonlinear ePWV-delirium relationship shown via RCS analysis.• KNN model with ePWV achieves AUC = 0.736 in validation cohort.• SHAP identifies RF, ARF, and ACEI as key predictors.• ePWV is a novel non-invasive biomarker for early delirium screening.