Cross-stress memory in plants: mobile RNAs, extracellular vesicles, and local-to-systemic signal integration

Causal Validation of Mobile RNA and Extracellular Vesicle Signals in Plants: Experimental Frameworks for Sequential Stress Acclimation.

Long-distance molecular transport contributes to coordination between locally stressed tissues and distal organs, but assigning causal systemic-signaling functions to mobile RNAs and extracellular vesicle (EV)-associated molecules remains experimentally challenging. This review critically evaluates the evidence require...

Plant EV small RNAs as programmable cross-kingdom signals: Mechanisms, evidence standards, and crop protection.

Plant extracellular vesicles (EVs) have emerged as candidate carriers of small RNAs that connect intracellular RNA regulation with apoplastic defense, intercellular signaling, and cross-kingdom communication. The field is advancing rapidly, yet its central mechanistic claims remain unevenly resolved because RNA detecti...

The miRNA-ROS interactome: Orchestrating plant resilience to environmental fluxes.

As sessile organisms, plants constantly face environmental stresses that disrupt reactive oxygen species (ROS) homeostasis. ROS function as critical signaling molecules orchestrating stress adaptation, while microRNAs (miRNAs) have emerged as master regulators of gene expression. Accumulating evidence reveals a bidirec...

Rapid Whole-Plant Signalling Under Compound Environmental Stresses: Systemic Integration, Stomatal Coordination and Stress Memory.

This review develops a mechanistic framework for rapid whole-plant stress signalling under compound environmental stresses and outlines an experimental pipeline combining live biosensors, electrophysiology, vascular imaging, spatial omics, perturbation genetics and crop phenotyping.

m6A-m5C epitranscriptomic regulation of plant stress memory and development: mechanisms and physiological effects

Epigenetic regulation and ROS signaling in plant stress adaptation: an integrated framework

This review examines the bidirectional interactions between epigenetic mechanisms and ROS homeostasis in plant stress adaptation, with a particular emphasis on drought resistance, and proposes that these interactions take the form of dynamic regulatory networks rather than one-way pathways.