This review systematically examines how histone modifications, including acetylation, methylation, phosphorylation, phosphorylation, ubiquitination, and SUMOylation regulate metabolic genes, and ATP‑dependent chromatin remodeling regulate metabolic genes.
This review comprehensively summarizes the multifaceted roles of major histone modifications, including acetylation, methylation, ubiquitination, phosphorylation, and emerging metabolism-linked acylations, in governing critical DNA-templated processes such as replication, transcription, and the DNA damage response.
Ling-Li Wang, Shi-Ying Li, Xiao-Yan Hu et al.· Precision Clinical Medicine· 0 citations
Cancer cells undergo extensive metabolic reprogramming to sustain rapid proliferation and adapt to heterogeneous tumour microenvironments. These metabolic alterations are tightly linked to epigenetic regulation, which reshapes gene expression and cellular signalling mechanisms. Among epigenetic regulators, histone deac...
Yu Hyun Jeon, Hyeyeong Seo, J. Youn et al.· Experimental and Molecular M...· 0 citations
This narrative review examines how alterations in fatty acid oxidation, lipid uptake, cholesterol metabolism and lipid-derived metabolites converge on the sirtuin family of NAD+-dependent enzymes to regulate epigenetic states in cancer.
F. Lagunas-Rangel· Molecular Biology Reports· 0 citations
This review examines the bidirectional interactions between epigenetic mechanisms and ROS homeostasis in plant stress adaptation, with a particular emphasis on drought resistance, and proposes that these interactions take the form of dynamic regulatory networks rather than one-way pathways.
N. Bhanbhro, Q. Bakhsh, Shengdixin Shi et al.· Theoretical and Applied Gene...· 1 citation
This synthesis provides a framework for understanding how SUMOylation links metabolic stress to tissue-specific aging trajectories and therapeutic potential and evaluates emerging translational approaches that highlight both the opportunities and challenges of targeting SUMO-regulated stress responses in aging.
Xin-Yue Liu, Shuang Chen, Dong-Can Liu et al.· Ageing Research Reviews· 0 citations
