TL;DR
The efficiency of the antibacterial surfactin synthesized from a mangrove bacterium B. velezensis ES8024 against Aeromonas hydrophila ATCC 35654 and the effectiveness of the compound with respect to future climate change and heavy metal contaminated environment are revealed.
The identified endophytic bacterium B. pumilus is demonstrated as a source of as a potent antibacterial, antioxidant, and anticancer agent with a key role in providing insights into their impact on the host as well as their applications in the field of pharmaceuticals.
Findings indicate that penicillic acid inhibits V. parahaemolyticus and is associated with concentration-dependent impairment of cell-envelope integrity.
Evidence is provided that endophytic fungi from S. sonchifolius, notably F. verticillioides (DY5), can serve as potential sources of bioactive compounds with pharmaceutical relevance and meet the threshold of bioactive extracts.
The oligotrophic and saline environment supported a diverse community of halotolerant bacteria with significant biosurfactant production potential, underscoring implications for bioremediation and aquaculture.
The results revealed that An-EtOAcE exhibited broad-spectrum antimicrobial effects, with maximum inhibition against E. coli, and significant α-amylase and α-glucosidase enzyme inhibition in antidiabetic activities with IC90 of 125.90 ± 1.32 and 80.60 ± 2.74 µg/mL, respectively.
Overall, this study reports the first isolation of M. circinelloides from Egyptian C. sinuosa and highlights its potential as a promising source of bioactive metabolites with enhanced antibacterial activity and multifunctional properties suitable for pharmaceutical and dermocosmetic applications.
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