TL;DR
Findings support phytic acid-functionalized HEMA cryogels as promising, antibiotic-free and biocompatible candidates for mitigating biofilm-associated wound infections.
OBJECTIVE This study aims to develop a novel biogenic nano-formulation of copper oxide nanoparticles (CuO-NPs) using the Moroccan medicinal plant Inula viscosa to address critical challenges in wound care, specifically infection risks and coagulation disorders. SIGNIFICANCE By utilizing bioactive plant compounds as n...
A novel multifunctional hydrogel (CGBAgel) was fabricated with glutathione-modified carboxymethyl cellulose and bovine serum albumin as matrixes, holding great clinical translation potential for bacteria-infected wound management.
Oxidative stress and bacterial infections can lead to compromised tissue regeneration in chronic wounds. Since traditional treatments are often ineffective, in this study a hydrogel based on two inulin derivatives, called dcINU-TA-NS, was design as multifunctional wound dressing platform with in vitro Anti-Staphylococc...
A novel integration of capsaicin-mediated silver nanoparticles within a chitosan–alginate biopolymeric matrix is introduced, providing a multifunctional strategy that enhances both antimicrobial efficacy and wound regeneration compared to conventional systems.
Diabetic wound healing remains a challenge due to persistent oxidative stress, defective angiogenesis and bacterial infection. Herein, a multifunctional hydrogel Y/PDA@HAPLL was engineered via Schiff-base crosslinking between oxidized hyaluronic acid (OHA) and ε-poly-L-lysine (ε-PLL) and incorporating Y-27632 (Y, R-tra...
A modular polyacrylamide-co-acrylic acid N-hydroxysuccinimide (PAM-AA-NHS) hydrogel platform offering chemical versatility and mechanical tunability for precision care is reported, with favorable hemocompatibility, cytocompatibility, and significant in vivo wound healing performance.
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