Endolysosomal iron-associated vesicular changes and ferroptosis-related vulnerability in VPS13A-knockdown cells

Kensuke Imamura Yoshiaki Nishizawa Kazutaka Sainohira Hitoshi Sakimoto Yuka Urata Natsuki Sasaki K. Arai Hanae Hiwatashi Izumi Yokoyama A. Sano Masayuki Nakamura

Aug 2026 · Molecular Biology Reports · Vol 53 · 0 citations · 31 references

Medicine

TL;DR

It is suggested that lysosome-associated vesicular changes in VPS13A-KD cells may be associated with altered iron handling, consistent with the previous finding of impaired Fe(II) efflux.

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