miR-584-5p suppresses Aβ1-42-induced apoptosis in Alzheimer's disease cell model via targeting of HDAC1.
Medicine
Similar papers
Jul 2026
LncRNA DLX6-AS1 Regulates the Pathological Process Related to Alzheimer’s Disease via miR-204-5p
Serum DLX6-AS1 is a potential biomarker for early diagnosis and assessment of AD, and regulates Aβ-induced neuronal damage and tau phosphorylation by targeting miR-204-5p, offering a new mechanism target for AD molecular therapy.
Minggang Jiang, Yang Lin, Liping Wang et al.
· Neuromolecular medicine · 0 citations
Open access
Aug 2026
LncRNA FBXL19-AS1 regulates the miR-650/ITGB3 axis to drive pathological progression in Alzheimer’s Disease
FBXL19-AS1 appears to interact with and modulate miR-650, thereby affecting ITGB3 expression and potentially participating in the pathological progression of AD.
Jie Dou, Yan-Ping Zhu, Zili Du et al.
· Hereditas · 0 citations
Aug 2026
Let-7d-5p improves mouse cognitive function by targeting bach1 in Alzheimer's disease.
Let-7d-5p alleviates cognitive deficits in AD by inhibiting Aβ deposition and neuronal apoptosis through targeting bach1, and bach1 upregulation counteracted the inhibitory effects of let-7d-5p overexpression on Aβ1-42-induced cellular injury.
Yu Liu, Lang Peng, Ming Li et al.
· Experimental Neurology · 0 citations
Jul 2026
Mechanistic and functional study of lncRNA SNHG3/miR-128-3p/UBR5 axis in neuroinflammation in Alzheimer's disease.
This study is the first to elucidate that SNHG3 could regulate microglial polarization and neuroinflammation through the SNHG3/miR-128-3p/UBR5 axis.
Xin-An Zhu, Huijie Lu, Yumei Liu et al.
· The journals of gerontology.... · 0 citations
Aug 2026
The SNHG16/miR-485-5p axis exacerbates neuronal injury in pediatric temporal lobe epilepsy.
SNHG16 is highly expressed in pediatric TLE and has certain diagnostic potential and exacerbates epilepsy-related neuronal damage by binding to and suppressing miR-485-5p function, which provides novel insights into understanding the disease mechanism.
Xuemin Ding, Hai-Xia Luo
· Epileptic disorders · 0 citations
Jul 2026
Role of Abca7-related microglial responses in linking type 2 diabetes mellitus to Alzheimer's Disease progression: Evidence from single-cell transcriptomic analysis and experimental validation in animal and cell models.
Results suggest Abca7 may play a linking role in the microglial response between T2DM and AD, which is partly supported by in vivo and in vitro results of its effect on the hyperactivation of microglia in AD-like pathologies.
Ming Cheng, Xin Zheng, Ya-Dong Wei et al.
· European Journal of Pharmaco... · 0 citations