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Open access

RIG-I–MAVS–NOXA axis coordinates antiviral defense and apoptosis during parahenipavirus infection

Shivani Rajoriya Divya Misra S. Yu Altanzul Bat Ulzii Hennisa Hennisa Tae-Wook Kang Hye Jin Shin Yeonsu Oh Carolina B. López Won-Keun Kim
Aug 2026 · bioRxiv · 0 citations
Biology

TL;DR

It is found that GAKV is primarily detected by the innate immune sensor retinoic acid-inducible gene I, which activates antiviral signaling through the adaptor protein mitochondrial antiviral signaling protein (MAVS) and initiates type I interferon (IFN) responses.

DOI Semantic Scholar
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