THE RELATIONSHIP OF BLOOD PRESSURE CHANGES TO THE INCIDENCE OF IONV IN HYPERTENSIVE PATIENTS WHO UNDERWENT REGIONAL ANESTHESIA

Abstract

Spinal anesthesia produces sympathetic blockade, which can cause vasodilation and intraoperative hypotension (IOH), one of the most common hemodynamic complications. Intraoperative hypotension may be defined using absolute thresholds, such as mean arterial pressure (MAP) <65–70 mmHg, or relative thresholds, such as a decrease of >20% from baseline. Hemodynamic changes during spinal anesthesia may contribute to intraoperative nausea and vomiting (IONV). This study aimed to determine the relationship between intraoperative blood pressure changes and the incidence of intraoperative nausea and vomiting (IONV) in hypertensive patients undergoing spinal anesthesia. This study used an analytical observational design with a cross-sectional approach. A total of 59 hypertensive patients undergoing surgery under spinal anesthesia were recruited using consecutive sampling. The independent variable was intraoperative blood pressure change, while the dependent variable was IONV. The relationship between the variables was analyzed using Spearman’s rho correlation test. There was a statistically significant correlation between intraoperative blood pressure changes and IONV (Spearman’s ρ = −0.538, p < 0.001). A statistically significant correlation was found between intraoperative blood pressure changes and IONV among hypertensive patients undergoing spinal anesthesia. These findings highlight the importance of careful intraoperative hemodynamic monitoring in this population.