TL;DR
TLR4 and MYD88 were elevated significantly in BC group with strong discriminating power for BC group, estimating their association with BC progression.
The CD24-EDN1-NFκB axis has a crucial role in PTX resistance in TNBC, according to this study, offering a new therapeutic target for treating chemotherapy resistance.
Toll-like receptors (TLRs) play a significant role in the tumor microenvironment, including in brain tumors, as their activation can both support an anti-tumor response and promote tumor progression through chronic inflammation. However, the precise mechanisms of TLR action have not been fully elucidated, likely due to...
ULBP1 may serve as a potential novel prognostic biomarker in BC, and targeting ULBP1 may provide a new therapeutic strategy for BC.
Breast cancer is the leading cause of diagnosed cancer cases in Iraq, making it the leading cause of cancer-related death among Iraqi women. BCs are characterized by genetic heterogeneity and complexity because of the overlap of numerous genes. Therefore, it is important to study genetic variants that increase the risk...
An association of STK35L1 and EGFR in BC is reported, highlighting STK35L1 as a potential prognostic biomarker and therapeutic target and suggesting that EGFR-STAT3 signaling may regulate STK35L1 and EGFR expression.
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