Early-gestational binge ethanol exposure induces persistent motor dysfunction associated with cerebellar redox and cytokine dysregulation in rat offspring.

P. F. S. Mendes Daiane Claydes Baia-da-Silva Vinicius Ruan Neves Dos Santos Leonardo de Oliveira Bittencout Lucas Villar Pedrosa da Silva Pantoja Luanna de Melo Pereira Fernandes R. Burbano Cristiane Socorro Ferraz Maia R. R. Lima

Sep 2026 · Toxicological Sciences · Vol 209 · 0 citations

Medicine

TL;DR

It is demonstrated that brief binge-like EtOH exposure during early gestation is sufficient to induce persistent motor dysfunction accompanied by cerebellar redox imbalance and cytokine dysregulation, with evidence of sex-dependent behavioral susceptibility.

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