Longitudinal impact of sodium bicarbonate therapy on health-related quality of life in pre-dialysis chronic kidney disease with metabolic acidosis: a pragmatic trial in Malaysia
Sep 2026· Quality of Life Research· Vol 35· 0 citations· 21 references
Medicine
TL;DR
Sodium bicarbonate therapy did not improve HRQoL in pre-dialysis CKD patients with MA following initiation of sodium bicarbonate therapy, highlighting the practical challenges and limitations of treat-to-target alkali therapy in routine clinical practice.
Chronic kidney disease requiring maintenance hemodialysis is associated with substantial physical, psychological and social burden, leading to impaired quality of life. Therefore, it is of interest to assess the QoL among patients with CKD undergoing hemodialysis and evaluate its association with clinical, biochemical,...
Background: Chronic kidney disease (CKD) is increasingly recognized as a risk factor for cognitive impairment, which may affect treatment adherence, daily functioning, and quality of life. Cognitive dysfunction may begin in earlier CKD stages and worsen with disease progression, but data across the full CKD stage spect...
Prashant J. Patil, Pratik Tripathi, Kishalay Mahajan· National journal of medical...· 0 citations
Background/Objectives: Chronic kidney disease (CKD) is a major cause of morbidity and mortality. Evidence on routine management and patient-reported outcomes in Greece is limited. The SPIRIT study assessed real-world treatment patterns, disease management, and quality of life (QoL) among CKD patients in Greece. Methods...
Evangelia Ntounousi, K. Stylianou, S. Marinaki et al.· Journal of Clinical Medicine· 0 citations
Background: Sodium-glucose cotransporter-2 (SGLT2) inhibitors have been shown to reduce the rate of chronic kidney disease (CKD) progression and provide cardioprotective benefits beyond glycemic control. However, evidence regarding their effects on kidney disease progression in advanced CKD patients remains limited. Ob...
Background: Chronic Kidney Disease (CKD) represents a major global health concern, leading to serious outcomes such as progression to End-Stage Renal Disease (ESRD), complications arising from reduced kidney function, and a heightened risk of Cardiovascular Disease (CVD) Serum albumin is a marker of malnutrition as wel...
Farhad Hussain, P. Dutta· Journal of Chittagong Medica...· 0 citations
AIMS
To assess the demographic, clinical, behavioural, and treatment factors associated with health-related quality of life (HRQoL) in heart failure (HF), examine the association between HRQoL and mortality, and evaluate changes in HRQoL over 1-year.
METHODS
We analysed the ESC EORP Heart Failure III Registry, includ...
M. Walli-Attaei, L. Lund, R. Luengo-Fernandez et al.· European Journal of Heart Fa...· 0 citations
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