Aug 2026· Current Genetic Medicine Reports· Vol 14· 0 citations· 32 references
TL;DR
This study found that LINC02257 and LINC00659 are upregulated in BC and are associated with malignancy-related genes and patient survival, suggesting their potential as therapeutic targets and prognostic biomarkers.
This computational study identifies several candidate lncRNAs associated with clinical outcomes in breast cancer, which should be interpreted as preliminary candidates, which require future validation and functional studies to determine their biological roles and evaluate their potential as prognostic biomarkers.
M. Acencio, Xin-Hui Wang, Flavia R. Rotea Mangone et al.· International Journal of Mol...· 0 citations
This study investigated how LINC00673-V4 drives CRC proliferation by modulating the Hippo-Yes-associated protein (Hippo-YAP) signaling pathway and identified LINC00673-V4 as an isoform-specific oncogenic lncRNA in CRC.
Wei Lu, Jiamin Zhong, Yunxiang Zhou et al.· Frontiers in Bioscience· 0 citations
LINC00578 rs7430456 is associated with breast cancer susceptibility, and LINC00578 promotes TNBC progression via sponging miR-143-5p, being a potential biomarker and therapeutic target for breast cancer, particularly TNBC.
Jing Zhai, Wei Wu, Xiao-Yun Mao et al.· Hereditas· 0 citations
C17orf75 plays an important role in LIHC progression by regulating cell cycle progression and EMT, and it may serve as a potential therapeutic target for LIHC.
Hao Liang, Nan-Bin Liu, Yibing Melody Zhai et al.· Frontiers in Immunology· 0 citations
Findings establish LINC00460 as an oncogenic driver in ccRCC and a promising target for both diagnosis and precision therapy and identifies cinchonine and iproniazid as candidate therapeutic agents.
Bo Dong, Songtao Liu, Wenyu Wang et al.· American journal of translat...· 0 citations
Analysis of the impact of LINC01133 depletion on malignant phenotypes and on the expression of migration- and invasion-associated genes using the Hs578T triple-negative breast cancer cell line indicates that LINC01133 acts as a potential fine regulator of in vitro migration and invasion processes in TNBC.
H. C. Jesus-Ferreira, Leandro Teodoro, Ana C. O. Carreira et al.· bioRxiv· 0 citations
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