Qualitative evidence is provided that NMs induced significant biochemical, oxidative, and genotoxic effects in rats and mice, with toxicological responses being influenced by NMs characteristics and exposure conditions, supporting more accurate hazard evaluation and the safe application of nanomaterials.
The findings demonstrate that Al₂O₃-NPs disrupt cellular homeostasis in insects through oxidative, apoptotic, and detoxification-mediated mechanisms, providing important insights into the mechanistic toxicology and environmental implications of aluminum-based nanomaterials.
M. Germoush, Maged M. A. Fouda, Shaymaa H. Mahmoud· Bulletin of the Chemical Soc...· 0 citations
Titanium dioxide nanoparticles (TiO₂ NPs) are extensively utilized in biomedical and pharmacological sectors; however, they may interact with biological systems causing various risks. Therefore, the present study assessed the role of surface modification by either chitosan (CS) or silica (Si) in mitigating TiO₂ NPs-ind...
Isra Elhussein, E. Hassanen, Khaled Y. Farroh et al.· Toxicology and Applied Pharm...· 0 citations
Under the present experimental conditions, repeated inhalation exposure to the tested fragrance formulation induced systemic oxidative stress and multi-organ physiological and molecular alterations in rats, and vitamin E supplementation attenuated several of these alterations but did not fully restore normal levels.
N. Al-Sowayan, D. Al-Shebel· Frontiers in Pharmacology· 0 citations
Zinc oxide nanoparticles (ZnO-NP) are widely used due to their enhanced biological activity compared to the bulk counterpart (ZnO-BK), raising concerns about potential toxic effects on living organisms and the environment. This study investigated the toxicity of ZnO-NP and ZnO-BK using alternative in vitro and in vivo...
C. Araújo-Lima, Magno Maciel-Magalhães, Marcela Correia da Rocha Honorato et al.· ACS Omega· 0 citations
Abstract Copper oxide nanoparticles (CuONPs) have attracted considerable attention in biomedical research owing to their unique physicochemical properties, high surface reactivity, and versatile biological activities. Their nanoscale dimensions have enabled diverse applications in antimicrobial therapy, anticancer trea...
Hiba Muhammed, A. Nemmar· International Journal of Nan...· 0 citations
Bisphenol A (BPA) and its analogs are widely recognized for their use in industry and plastic manufacturing. Consequently, humans and animals are continually exposed to various substances in their daily lives. This review evaluates the hepatic toxicity of BPA and its analogs in mice and rats, with particular emphasis o...
S. Bagdatli, M. Canik, Gizem Gencay et al.· Journal of Applied Toxicolog...· 0 citations
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