TL;DR
Overexpression of circ_0070190 remarkably suppressed the proliferation, migration, and invasion of CC cells, and the circ_0070190/miR-587 regulatory axis may offer a potential novel target for the targeted therapy of CC.
BACKGROUND Circular RNA (circRNA) has been recognized as critical regulator in cancer progression. However, the mechanisms of circ_0081069 in breast cancer (BC) remain understood. The study was designed to elucidate the pathological significance and mechanism of circ_0081069 in BC. MATERIAL AND METHODS The expression...
As an oncogenic circRNA, hsa_circ_0001839 is critically implicated in gastric cancer progression and unfavorable patient outcomes, underscoring its dual application as a promising prognostic biomarker and a potential therapeutic intervention target.
ABSTRACT Due to the late stage at which most gastric cancer patients are diagnosed, the prognosis is often poor. Current treatments have limited efficacy for advanced cases. This study delves into the involvement of circARID1A and the mechanisms behind its role in gastric cancer progression. GES-1 cell line and GC cell...
Background: Circular RNAs (circRNAs) are recognized as critical regulators of gastric cancer (GC) progression. Nevertheless, the biological function of circ_0088302 in gastric cancer and its epitranscriptomic regulatory mechanism remain unclear. Methods: The expression of circ_0088302 was analyzed based on plasma circR...
MicroRNA-2110 has been implicated in cancer, but its expression and function in gastric cancer (GC) remain understudied. This study aims to explore the role of miR-2110 in GC and its regulation of IGF1R. RT-qPCR was used to measure miR-2110, IGF1R expression in 138 paired GC and adjacent normal tissues. Ex...
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