Neuroprotective effects of myricetin against rotenone-ınduced parkinsonian neurotoxicity: a multidimensional analysis in rats

Neuroprotective Effects of Celastrus paniculatus Seed Oil in Rotenoneinduced Parkinson's Disease in Wistar Rats.

INTRODUCTION Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by motor and cognitive impairments associated with oxidative stress, mitochondrial dysfunction, neuroinflammation, and degeneration of dopaminergic neurons. Celastrus paniculatus (CP), Jyothshmati, possesses antioxidant and...

Neuroprotective effects of dapansutrile in rotenone-induced parkinsonism: targeting NLRP3/caspase-1, NF-κB, Nrf2/HO-1, and PINK1/Parkin pathways.

Neuroprotective effect of Carnosic acid in Rotenone induced Parkinson’s disease in mice

Background/Introduction: Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by dopaminergic neuronal loss, oxidative stress and mitochondrial dysfunction. Current therapies mainly provide symptomatic relief without preventing disease progression. Carnosic acid (CA), a natural phenolic di...

Neuroprotective effects of oleuropein on dopamine level and caspase-3 activity in zebrafish model of Parkinson’s disease

Parkinson’s disease (PD) is characterized by the progressive loss of dopaminergic neurons in the substantia nigra, largely driven by oxidative stress-mediated apoptosis. Caspase-3 acts as the central executioner in this cell death pathway. While oleuropein, a phenolic compound from Olea europaea , is known for...

Neuroprotective Potential of Boric Acid in a Rotenone-induced in Vitro Parkinson’s Disease Model

Findings demonstrate that BA exerts a significant neuroprotective effect against rotenone-induced cytotoxicity by enhancing cell survival and modulating apoptosis-related pathways, suggesting a promising candidate for mitigating PD-associated neuronal damage.

Protective Effects of Cubebin on Neuroinflammation, Neurotransmitter Depletion, Mitochondrial Dysfunction, and Motor Disability in Parkinsonian Rats

Parkinson’s disease (PD) is an advanced neurodegenerative state with diverse degeneration of dopaminergic neurons, oxidative stress, mitochondrial dysfunction, and neuroinflammation. The present study aimed to evaluate the neuroprotective effect of cubebin against rotenone-induced Parkinsonism disability in Wistar rats...