Integrative transcriptomic, spatial and functional-genomic analysis identifies a UFMylation-related vascular-stromal program and prioritizes WWTR1 in glioblastoma

Jun-Qing Yan Jing-Liang Ye Wen-Bo Qian Jun-Le Zhu Zhi-Ping Wan Hao-Heng Wang Xiang-Tian Meng Jin-Mao Gu Feng Chen Chun Luo

Sep 2026 · Functional & Integrative Genomics · Vol 26 · 0 citations · 38 references

Medicine

TL;DR

Findings define an ER-stress/mesenchymal-weighted, UFMylation-related vascular-stromal transcriptional association and nominate WWTR1 for experimental testing.

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