Virtual reality mindfulness-based cognitive therapy for reducing psychological distress in people with depression and/or anxiety symptoms: two uncontrolled feasibility studies
Aug 2026· Pilot and Feasibility Studies· 0 citations
Abstract
Group mindfulness-based cognitive therapy (MBCT) is recommended for the treatment of subthreshold-to-mild depressive symptoms. Timely access to MBCT, however, is limited by accessibility issues. Self-help MBCT can overcome these issues, but is associated with poorer engagement. Incorporating virtual reality into self-help MBCT (VR-MBCT) may improve engagement, but relatively little is known about its feasibility and acceptability. Consequently, the aims of this study were to examine the acceptability, feasibility and preliminary signals of efficacy of VR-MBCT for reducing psychological distress in people with depression and/or anxiety symptoms.
In two uncontrolled feasibility studies, participants aged ≥ 18 years with mild-to-moderately severe symptoms of depression and/or anxiety were recruited via self-referral. Participants received five VR-MBCT sessions (totalling approximately two hours in duration) each week for 8 weeks plus usual care. Co-primary outcomes were feasibility (recruitment, retention and data completion) and acceptability (course completion and satisfaction with VR-MBCT) in both studies. Secondary outcomes included measures of depression, anxiety, mental well-being and mindfulness, assessed at pre- and post-intervention.
In Study 1, 35 participants (100% of the target) were recruited, 22 participants (63%) were retained, 20–22 participants (57–63%) completed outcome measures at both timepoints, and 18 participants (51%) completed 4 weeks of VR-MBCT. In Study 2, 48 participants (96% of the target) were recruited, 26 participants (54%) were retained, 23–26 participants (48–54%) completed outcome measures at both timepoints, and 22 participants (46%) completed 4 weeks of VR-MBCT. Satisfaction with VR-MBCT was high in both studies. Data were suggestive of improvements in anxiety, depression, mental well-being and mindfulness from pre- to post-intervention in both studies. Rates of reliable improvement were 77–90% in Study 1 and 62–70% in Study 2.
There was good evidence of the acceptability of VR-MBCT with respect to course satisfaction and feasibility in terms of recruitment. Although consistent with previous studies, findings suggested that further improvements could be made regarding retention/attrition, data completion and initial engagement. Preliminary signals of efficacy suggested that VR-MBCT may reduce psychological distress and improve mental wellbeing and mindfulness in people with depression and/or anxiety symptoms. However, results should be interpreted with caution due to study limitations.
Abstract Background Chronic pain (CP) is a complex and prevalent public health condition that significantly impacts physical functioning, psychological well-being, and quality of life. Traditional biomedical treatments often provide limited relief, highlighting the need for integrative approaches. Biopsychosocial inter...
S. Ghai, Sabrina Cavallo, Mathieu-Joël Gervais et al.· JMIR Formative Research· 0 citations
Abstract Background Many adolescents experience elevated stress and anxiety; yet, access to effective psychological support is limited. Brief digital mental health interventions, such as slow breathing (SB) and detached mindfulness (DM), offer a potentially scalable approach to promoting emotion regulation in daily lif...
R. Akdağ, Anja van der Voort, Lisa Tessensohn et al.· JMIR Formative Research· 0 citations
OBJECTIVES
This study evaluated the effectiveness of an integrated, application-supported mindfulness-based cognitive therapy (MBCT) programme in reducing depressive symptoms among adolescents with non-suicidal self-injury (NSSI).
METHODS
An open-label, two-arm randomized controlled trial was conducted in two public...
Russunan Jantarapakdee, R. Upasen, Penpaktr Uthis et al.· British Journal of Clinical...· 0 citations
BACKGROUND
Chronic low back pain (CLBP) is common and often refractory to existing treatments, necessitating long-term opioid therapy, which has substantial risks. Mindfulness-based (MBT) and cognitive behavioral (CBT) therapies are safe and can be effective for CLBP.
AIMS
To better understand how MBT and CBT may hel...
Douwné L. Müller, Eric L. Garland, Robert R. Edwards et al.· Pain Practice· 0 citations
Self-compassion-based virtual avatar therapy demonstrated preliminary feasibility and tolerability in patients with MDD, and exploratory analyses suggested increases in several dimensions of presence, embodiment, and perceived comfort across sessions.
Xiao He, Yong Xu· Frontiers in Virtual Reality· 0 citations
Both MBIs benefitted participants across subgroups, with limited evidence for differential effects by gender or mental health diagnoses, and further research is needed to more systematically determine whether MBIs can be optimized for key subgroups.
C. Calvert, Emily M. Hagel Campbell, Lee J. S. Cross et al.· The Clinical Journal of Pain· 0 citations
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