Clinicians are provided with a structured, evidence-based framework that identifies specific clinical scenarios where molecular diagnostics, host-response biomarkers, and three-dimensional imaging may meaningfully modify periodontal treatment decisions, supporting the operationalisation of precision approaches in daily practice.
Emerging biomarkers are fundamental for the transition to precision medicine in IBD, aiming to enhance pathogenesis understanding, personalize therapies, and improve patient quality of life, establishing pathways for more effective, individualized management approaches.
Matheus Querino da Silva, João Daniel de Souza Menezes, José Luis Esteves Francisco et al.· PLoS ONE· 0 citations
Objectives: To synthesize current evidence regarding advances in periodontal diagnosis and therapy, with emphasis on molecular biomarkers, omics technologies, microbiome profiling, digital imaging, and artificial intelligence-based analytical models that support the transition toward precision periodontology. Methods:...
Tatiana Chacón, Ó. Zuluaga-López, Gloria María Sandoval-Llanos et al.· Biomedicines· 0 citations
This Review proposes pathway-focused biomarkers as clinically translatable signatures that preserve biological mechanisms while enabling practical measurement, and outlines how pathway enrichment, network analysis, and multi-omic integration can identify these programs, and how feature selection can derive parsimonious...
L. V. Van Nynatten, Hira Raheel, J. Basmaji et al.· Critical Care· 2 citations
This review systematically examines the current application of multi‐omics biomarkers in genetic neuromuscular diseases and provides an in‐depth analysis of the multifaceted barriers encountered during the translation process, including technical hurdles, clinical validation complexities, data interpretation challenges...
Su-Ming Zhang, Xiao-Ling Lang, Lun-Xin Liu· Human Mutation· 0 citations
The concept of precision endodontics represents a potential evolution from conventional 'one-size-fits-all' approaches to more tailored interventions guided by extensive omics data, and the synergistic integration of omics and AI may provide a roadmap for developing the next generation of biologically individualised en...
M. Turky, P. Cooper, P. Dummer· International Endodontic Jou...· 0 citations
It is concluded that precision medicine in RA will require integrated biomarker panels combining clinical, pharmacological, molecular, and synovial tissue data, and the development of scalable, externally validated, and clinically interpretable models capable of assigning synovial endotypes and supporting mechanism-bas...
N. A. Batashkov, E. Gerasimova, D. Gerasimova et al.· Frontiers in Immunology· 0 citations
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