TL;DR
HHT and Tan IIA combined therapy synergistically suppressed lymphoma progression by downregulating the Akt/MMP signaling pathway, suggesting their use in treating lymphomas.
T-cell lymphoma (TCL) is a malignant tumor caused by abnormal proliferation of T cells, and its specific pathogenesis remains unclear. Currently, there is still a lack of highly effective therapeutic agents in clinic. As a semi-terpene lactone compound, Alantolactone (ATL) is mainly used to treat diseases such as asthm...
Findings suggest that Mumio exerts anticancer effects through oxidative stress-mediated apoptosis and modulation of ferroptosis pathways, suggesting its potential use alongside standard therapy.
Fibrosarcoma is a rare and aggressive soft tissue sarcoma with limited therapeutic options and poor outcomes in advanced disease. Family with sequence similarity 111 member B (FAM111B) has emerged as a pro-tumorigenic factor associated with dysregulated cell survival and proliferation. Cannabidiol (CBD), a non-ps...
DA elicits a biphasic cellular response in U937 leukemia cells, characterized by transient cytoprotective autophagy followed by apoptotic cell death mediated through dysregulation of Bcl-2/Bax and suppression of the PI3K/Akt pathway, indicating that DA is a promising candidate for novel antileukemic therapeutic strateg...
Enoxaparin exhibits multifaceted anticancer effects by promoting apoptosis and autophagy, selectively modulating inflammatory pathways, and reducing oxidative DNA damage in breast and liver cancer cells.
Results suggest that rFgStefin-1 promotes apoptosis in leukemic cells while exerting limited effects on normal cells under the tested conditions, and these findings were supported by both qRT-PCR and Western blot analyses.
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