In Vitro Development and Characterization of a Chitosan/PVA/Starch Hydrogel Film Incorporating Zinc Oxide Nanoparticles and Syzygium cumini Extract: Physicochemical, Antimicrobial, and Cytocompatibility Evaluation
Preliminary in vitro evidence is provided for S3 as a candidate hydrogel for infection-resistant wound-contact applications and claims relating to implant-associated infection management require dedicated in vivo biofilm and implant-model validation studies not yet performed here.
A hydrogel of chitosan, hydroxypropyl methylcellulose, and propylene glycol, incorporating lyophilized hAM particles to combine the hydrogel's physicochemical properties with hAM's bioactivity shows promising properties for wound dressings.
Zahra Chegeninezhad, M. Setayeshmehr, M. Zeinalian et al.· Biochemical and Biophysical...· 0 citations
Woven fibres loaded with an AMB/hydroxypropyl-γ-cyclodextrin inclusion complex enables sustained above-MIC AMB delivery from a dual-crosslinked biopolymeric dressing, providing in vitro proof-of-concept for Candida- infected chronic wounds, pending cytotoxicity and in vivo validation.
Rahmat Setiady Tasman, Wildan Khairi Muhtadi, Destria Indah Sari et al.· International journal of pha...· 0 citations
Overall, ZnONPs improved antibacterial activity, HAp provided the most favorable cytocompatibility and stability profile, while GONs showed a comparatively higher hemolytic response, highlighting the importance of nanoparticle selection in designing PVA/SA hydrogel scaffolds for tissue-contact applications.
N. Abuhamed, E. Dinçer, K. Öksüz· ACS Omega· 0 citations
A novel multifunctional wound dressing by integrating Petroselinum crispum (parsley, PS) extract and zinc ascorbate-based metal-organic frameworks (MOFs) into a polyvinyl alcohol (PVA) nanofibrous matrix that combines biodegradability, biocompatibility, and enhanced bioactivity for wound healing is reported.
Shimaa Husien, Rana R. Haikal, Eman A. Khalil et al.· Journal of Biological Engine...· 0 citations
The developed wafer showed strong potential as an antibacterial wound dressing, providing controlled drug release along with fast-acting relief from bacterial infections and the anti-microbial potential of wafers was confirmed using the disc diffusion method.
S. Chowdhury, Syed Mahmood, M. A. Mirza et al.· Scientific Reports· 1 citation
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