Jul 2026· International Journal of Drug Delivery Technology· Vol 16· 0 citations· 18 references
TL;DR
Inhalation sedation was more effective than oral sedation in improving children's dental experience and compliance during procedures, and support the preferential use of inhalation sedation as a behavior management strategy in pediatric dentistry.
Abstract
Background: Dental anxiety and uncooperative behavior are common challenges in pediatric dentistry and can
negatively affect treatment outcomes and future dental attendance. Sedation techniques are frequently employed
to reduce anxiety, improve cooperation, and enhance children's overall dental experience. However, evidence
comparing the impact of different sedation techniques on children's experience and compliance remains limited.
Objective: To compare the effects of inhalation sedation and oral sedation on children's experience and
compliance during dental procedures.
Methods: This prospective comparative observational study included 100 children aged 4–10 years requiring
dental treatment under sedation. Participants were divided into two groups: Group A (n = 50) received inhalation
sedation with nitrous oxide–oxygen, and Group B (n = 50) received oral sedation. Children's experience was
assessed post-procedure using a facial image scale, while compliance during treatment was evaluated using the
Frankl Behavior Rating Scale. Demographic and clinical variables were recorded. Data were analyzed using
descriptive statistics, chi-square tests, and logistic and ordinal regression analyses using STATA, with p < 0.05
considered statistically significant.
Results: Children in the inhalation sedation group demonstrated significantly higher rates of positive experience
and cooperative behavior compared to the oral sedation group. Logistic regression analysis showed that inhalation
sedation significantly increased the odds of cooperative behavior. Ordinal regression analysis also indicated a
significant association between inhalation sedation and improved experience scores, independent of age and
gender.
Conclusion: Inhalation sedation was more effective than oral sedation in improving children's dental experience
and compliance during procedures. These findings support the preferential use of inhalation sedation as a behavior
management strategy in pediatric dentistry
Dental anxiety in children represents a significant clinical challenge, adversely affecting patient cooperation, treatment outcomes, and long-term attitudes toward dental care. In recent years, increasing attention has been directed toward modern technologies designed to alleviate anxiety and pain during dental procedu...
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