Skip to content
Review Open access

Engagement with a Chatbot-based Intervention for the delivery of mailed at-home COVID-19 Testing: a Descriptive Log Analysis Study from the SCALE-UP II Trial

Jul 2026 · medRxiv · 0 citations
Medicine

TL;DR

Ordering of COVID-19 test kits among underserved patients who interacted with the chatbot was high, suggesting chatbots may represent a viable approach to reach underserved populations as a part of public health response in a pandemic.

Abstract

Background Promoting at-home tests (e.g., for COVID-19) using chatbots may be a novel and scalable way to improve uptake across underserved populations. Objective The objective of this study was to assess the navigational patterns (i.e., sequence of interactions) of underserved populations when using a chatbot designed to provide education on COVID-19 testing and free order access for at-home COVID-19 test kits. Methods The study was a descriptive analysis of the original data of the chatbot intervention of the SCALE-UP II trial, which compared different digital health modalities (i.e., chatbots versus simple text messages) to deliver free at-home COVID-19 test kits to minority populations in Utah. SCALE-UP II (registration numbers NCT05533918; NCT05533359) was a multisite, pragmatic clinical trial with patients randomized in a 2x2x2 factorial design (smartphone study) to receive (1) chatbot or text messaging, (2) the option to request patient navigation, and (3) intervention frequency every 10 or 30 days. All other participants were randomized in a 2x2 factorial design (nonsmartphone study) to receive the option to request patient navigation and intervention frequency every 10 or 30 days. Eligible patients (1) had an appointment at one of the participating community health centers (CHC) in the last 3 years, (2) were 18 years and older, and (3) had a valid cellphone number recorded in the CHC electronic health record (EHR). The trial enrolled 2117 in the smartphone study and 31,439 in the nonsmartphone study. In the smartphone study, the proportion of participants who requested test kits in the Chatbot arm was lower than in SMS text messaging. In the nonsmartphone study, test kits was higher if they were messaged every 10 days. Sources of funding included the National Institute on Minority Health and Health Disparities (NIMHD) of the US National Institutes of Health (NIH) grant number 5U01MD017421 and by awards from the National Cancer Institute of the NIH (P30CA042014) and the Huntsman Cancer Foundation. Results: Of 1,051 patients randomized to the chatbot intervention, 309 (29%) launched the chatbot, 196 (63%) interacted with it, and 186 (60%) started the COVID-19 test kit ordering process. Among those who launched the chatbot, 170 (55%) completed a test kit order. One patient (0.3%) accessed the chatbot educational content. The median age was 51, with 66% female, 54% Latino/a, 55% uninsured, and 86% located in an urban area. Conclusion: Ordering of COVID-19 test kits among underserved patients who interacted with the chatbot was high. Thus, chatbots may represent a viable approach to reach underserved populations as a part of public health response in a pandemic. All patients except one placed orders without reviewing educational content. Chatbot design should identify and minimize the number of steps for patients to achieve a specific goal.

Read PDF

Similar papers

Open access Jul 2026

Chatbot-based health interventions in low- and middle-income countries: effective access, early attrition, and design strategies from a mixed-methods study

Effective access is introduced as a complementary construct for digital health interventions requiring repeated participation and three design principles are proposed to test whether users can resume participation under platform constraints; reduce message burden without removing content; and treat re-engagement as a c...

Maxwell C. Klapow, P. Zinser, C. Facciolà et al. · 0 citations
Review Aug 2026

Patient Perspectives of the Barriers and Facilitators to Participating in Appointments by Choice: A Qualitative Study of a Patient-Initiated Follow-Up Implementation Pilot Using the Consolidated Framework for Implementation Research

People with RA described ABC as a feasible and acceptable model of care, with minimal barriers identified, and patients valued the flexibility of the ABC model, particularly those living at a distance and highlighted the responsiveness of the flare clinic and pharmacist support in medication adjustments.

Kiran Dhiman, M. Ester, Krista White et al. · 0 citations
Open access Jul 2026

A mixed-methods process evaluation of internet-delivered self-help Acceptance and Commitment Therapy for family carers of people with dementia (iACT4CARERS): engagement, mechanisms, and contextual factors.

Intervention implementation, contextual factors influencing engagement, contextual factors influencing engagement, and mechanisms of impact were examined, focusing on how participants engaged with intervention content and therapist support to produce expected changes.

Abbey Couchman, T. Katangwe-Chigamba, David Howe et al. · 0 citations
Review Aug 2026

Effectiveness of the recruitment strategies used in the Baby-Feed Online Trial, a trial to test an educational web application for caregivers to prevent excessive weight gain in infants.

Both recruitment strategies were crucial in recruiting the required sample within a short period with no socio-demographic differences, and these strategies were effective in recruiting a highly educated group.

Cristina Palacios, Alayne Gatto, Gabriella Reingevurts et al. · 0 citations
Open access Aug 2026

Improving Patient-Reported End-of-Life Data Capture: A Pilot Mixed-Methods Evaluation of an Electronic Patient Reported Outcomes Chatbot Platform Using Messaging Applications From Bereaved Caregivers in Chile.

ALVA achieved near-universal completion among registered caregivers (100% QODD; 95% including postinterview) with rapid, same-day questionnaire completion and feasible death-anchored timeliness, supporting scale-up and a comparative trial to optimize implementation and equity.

J. Retamales, Claudio Aracena, Laura Aguilera Beovides et al. · 0 citations
Open access Jul 2026

Evaluating the Efficacy of Electronic Screening, Brief Intervention, and Referral to Treatment (e‐SBIRT) for Gambling: An Online Pilot Randomised Trial

ABSTRACT Objectives To investigate the efficacy of electronic screening, brief intervention, and referral to treatment (e‐SBIRT) at improving gambling outcomes and increasing help‐seeking. Methods We conducted a two‐arm, randomised online pilot trial (n = 83) comparing an e‐SBIRT intervention with an active control ove...

Simon Wright, Martyn Quigley, Simon Dymond · 0 citations

We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.