Commentary on “Solubility Determination and Correlation of 2-Methyl-6-propionylnaphthalene in Pure Solvents and Binary Solvent Systems (Water + Methanol/Ethanol/ n -Propanol) from 278.15 to 318.15 K”

Abstract

In a recent article titled “Solubility Determination and Correlation of 2-Methyl-6-propionylnaphthalene in Pure Solvents and Binary Solvent Systems (Water + Methanol/Ethanol/n-Propanol) from 278.15 to 318.15 K” published in this journal, Li et al. reported the solubility behavior of 2-methyl-6-propionylnaphthalene (2,6-MPN) in ten pure solvents and three binary mixed solvents, and conducted a correlation analysis between the experimental solubility data and seven thermodynamic models. While their experimental work provides fundamental data for the crystallization of 2,6-MPN, significant inaccuracies are identified in the fitting parameters of the modified Apelblat equation and the λh equation. These inaccurate parameters lead to substantial deviations between calculated and experimental solubilities. This work systematically verifies the errors, analyzes their origins, and provides optimization suggestions, aiming to ensure the reliability of thermodynamic data for 2,6-MPN crystallization process design and solvent selection.