Comparative Metabolite Profiling and Bioactivity Evaluation of Pneumatophore-Derived Aspergillus Strains From Three Geographically Distinct Mangrove Ecosystems of India: Isolation of a New Dahejpyrone Derivative
Jul 2026· Current Microbiology· Vol 83· 0 citations· 37 references
Medicine
TL;DR
The land use land cover classes reveal a strong correlation of mangroves with microbial nature, and a first time report, new dahejpyrone (kavapyrone analog, 5) from Aspergillus niger.
The results revealed that An-EtOAcE exhibited broad-spectrum antimicrobial effects, with maximum inhibition against E. coli, and significant α-amylase and α-glucosidase enzyme inhibition in antidiabetic activities with IC90 of 125.90 ± 1.32 and 80.60 ± 2.74 µg/mL, respectively.
S. Jaast, Mohit Kumar, Anil Kumar· Archives of Microbiology· 0 citations
Results support the potential of P. chrysogenum extract as a biologically active anti-inflammatory preparation, pending additional mechanistic and translational studies.
Ahmed Sadoun, Hussien H. Elshikh, M. Elaasser et al.· Journal of Basic and Applied...· 0 citations
The genus Plenodomus remains relatively understudied, with limited reports regarding its specialized metabolites. In this study, the endophytic strain Plenodomus sp. IQ-2000, isolated from Tanacetum parthenium (L.) Schultz-Bip, was investigated following preliminary screenings that revealed a promising capacity to prod...
Carlos A. Fajardo-Hernández, Martha Isela Romero-Bazán, V. Reyes-Pérez et al.· Fitoterapia· 0 citations
Antifungal evaluation against the phytopathogen Colletotrichum gloeosporioides demonstrated that compounds 1 and 3 exhibited significant inhibitory activity, with EC50 values of 32.77 ± 1.12 μg/mL and 42.81 ± 1.01 μg/mL, respectively, both outperforming the positive control carbendazim.
H. Fan, Yinhan Teng, Jing-Jing Su et al.· Natural Product Research· 0 citations
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