TL;DR
Remimazolam did not appear to increase POD over the first 7 postoperative days compared with saline, although the study was not powered to detect modest differences.
Objectives: The objective of the study was to assess the effectiveness and safety of dexmedetomidine versus midazolam for sedation during regional anesthesia surgery. Methods: This prospective randomized comparative interventional study was conducted in the Department of Anesthesiology at a tertiary care hospital from...
Importance Postoperative delirium is a common and serious neurocognitive complication in elderly arthroplasty patients, with preoperative poor sleep as a key risk factor. Effective preoperative prevention strategies remain an urgent clinical need. Objective To assess preoperative intranasal dexmedetomidine for preventi...
INTRODUCTION Remimazolam tosylate is an ultra-short-acting benzodiazepine sedative and anaesthetic. The related drug, midazolam, is associated with delirium but it remains unclear whether remimazolam also promotes delirium. We tested the primary hypothesis that remimazolam is non-inferior to propofol for delirium in pa...
Remimazolam benzenesulfonate has more stable hemodynamics and a lower incidence of adverse reactions during total intravenous anesthesia in elderly patients undergoing LC, and shows benefits in early postoperative recovery, cognitive function, and pain control.
In this selected population of older patients undergoing ERCP, the remimazolam-esketamine regimen was associated with fewer composite SRAEs than propofol-fentanyl while achieving a similar anesthetic regimen success rate.
Remimazolam significantly shortened recovery time and reduced flumazenil use in elderly patients, which may reduce staff workload after ERCP; larger studies are needed to establish comparative safety.
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