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In vivo imaging of synaptic density in psychotropic-free adults with autism spectrum disorder: a [¹¹C]UCB-J PET study.

Masamichi Yokokura Taishi Tamayama Yosuke Kameno Toshiki Iwabuchi Takafumi Goto Ichiro Murata Taeko Harada Noritake Ichinohe Yasuomi Ouchi H. Yamasue
Aug 2026 · Molecular Psychiatry · 0 citations · 55 references
Medicine

TL;DR

The observed association between [¹¹C]UCB-J SUVR and RRB severity serves as a hypothesis-generating indicator of synaptic involvement of the behavioral rigidity in ASD, and highlights the complexity of ASD-related synaptic pathology.

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