Nocardia farcinica, as an uncommon cause of subcutaneous infection – Case report and literature review

Abstract

Abstract Introduction Nocardia is a rare group of opportunistic bacteria that normally causes infections in immunocompromised patients. It can involve multiple organ systems: most frequently the lungs, followed by the skin, central nervous system, bones, and joints. Within this group, Nocardia farcinica is among the most commonly identified pathogenic species. Case presentation We report the case of a 45-year-old male patient with a history of sensory-motor polyradiculoneuropathy of demyelinating origin who presented to the emergency department with an extensive soft tissue infection in the right popliteal region. The patient required multiple surgical procedures and multidisciplinary care. The patient also received prolonged, targeted antibiotic therapy, which resulted in complete recovery. Conclusions Nocardia farcinica is a rare opportunistic pathogen that mainly affects immunocompromised individuals and can cause severe systemic or localized infections. Early identification is crucial, as prompt surgical intervention combined with targeted antibiotic therapy is essential for favorable outcomes and helps prevent dissemination and other serious complications.