Epidemiologic and Histopathologic Features of Brain Tumors: A Two-Year Experience from a Single Center

Abstract

Objective: This study aimed to evaluate the demographic, anatomical, and histopathological characteristics of intracranial brain tumors surgically treated at our institution and to compare the results with previously published literature. Materials and Methods: In this retrospective single-center study, data from 143 patients who underwent surgical treatment for intracranial brain tumors at the Neurosurgery Clinic of Kanuni Sultan Süleyman Training and Research Hospital between January 1, 2024, and December 31, 2025, were analyzed. Patient age, sex, comorbidities, tumor location, tumor size, and histopathological diagnoses were evaluated. Descriptive statistical methods were used for the analysis. Results: Of the patients, 83 (58%) were male and 60 (42%) were female, with a mean age of 62±8.75 years. Tumors were located supratentorially in 83.9% of cases and infratentorially in 16.1%. Metastasis was the most common tumor type (30%). Among primary tumors, meningioma was the most frequent (26.5%), while glioblastoma was the most common primary malignant tumor (22.3%). Pediatric patients accounted for 6.3% of the cohort, with pilocytic astrocytoma and glioblastoma being the most prominent diagnoses in this group. Conclusion: The findings of our study demonstrate that the demographic and histopathological distribution of intracranial brain tumors is largely consistent with the existing literature. The high prevalence of metastatic tumors and glioblastomas underscores their clinical significance in the adult population. Further large-scale, multicenter studies are warranted to validate and expand upon these findings.