Open access
Free‐Breathing Hepatic Oxygen Extraction Fraction (OEF) Mapping Using Radial GESSE
Ke Zhang
S. Triphan
Felix T. Kurz
Cong-Cong Fu
Na Zhang
C. Ziener
M. E. Ladd
H. Schlemmer
Hans-Ulrich Kauczor
O. Sedlaczek
Medicine
Abstract
Noninvasive assessment of hepatic oxygenation is relevant for evaluating liver both in acute and long‐term liver pathologies. However, existing methods are limited to single‐slice acquisitions and require breath‐holding. This study aims to develop and evaluate a motion‐robust technique for whole‐liver oxygen extraction fraction (OEF) mapping using a radial gradient‐echo sampling of spin‐echo (rGESSE) sequence in combination with an artificial neural network (ANN) for quantification.