Skip to content

virus-specific immune responses in C57BL/6 mice by immunization with a modified recombinant adenovirus containing the chimeric gene, GcS0.7

· 0 citations · 30 references

TL;DR

The CAG hybrid promoter improved not only the expression level, but also the immunogenicity of the fusion protein, and may thus provide a promising strategy for HTNV vaccine research.

View source

Similar papers

Open access Jul 2026

A single-dose chimeric Newcastle disease virus (NDV)/chikungunya virus (CHIKV) is an effective CHIKV vaccine candidate

A Newcastle disease virus (NDV) vector vaccine candidate expressing the complete envelope (E3–E1) protein of chikungunya virus (CHIKV) successfully develops a novel vaccine candidate that utilizes Newcastle disease virus as a vector to express CHIKV antigens.

Qiu-Yan Zhang, Yang Zhang, Zhe-Rui Zhang et al. · 0 citations
Aug 2026

Dengue virus rNS3pro immunization is associated with the expansion of regulatory-like T-cell phenotypes in BALB/c mice.

Dengue virus rNS3pro immunization drives a robust expansion of multifaceted regulatory-like T-cell phenotypes, identifying the NS3 protease domain as a potential player in DENV immune evasion strategies.

V. Romero-Cruz, A. Ramos-Ligonio, Diana Lizzet Murrieta-León et al. · 0 citations
Jul 2026

[Construction of a chimeric cell model expressing human immunodeficiency virus-1 envelope protein based on transposon system and evaluation of chimeric antigen receptor t-cell cytotoxicity in vitro].

The HEK293T model stably expressing membrane-anchored HIV-1 gp160(ΔCT) model provides a robust platform for benchmarking the targeted recognition and cytotoxic activity of antiviral antibodies, agents, and CAR-T therapies in HIV research.

Jiarui Liu, Yang Gao, Changjun Wang et al. · 0 citations
Open access Aug 2026

Dual-expression-site fowl adenovirus 4 (FAdV-4) with high viral titer: a promising viral vector for multivalent poultry vaccines

The recombinant virus maintained wild-type-comparable titers while carrying 3606 bp of total foreign sequences, highlighting its dual-site advantage and potential as a multivalent poultry vaccine vector.

Zhi-Hui Tang, Wenjian Liu, Biao Xu et al. · 0 citations
Open access Jul 2026

Enhanced replication and immunogenicity of a genome-modified non-replicating vaccinia virus Tiantan strain for robust low-dose protection in mice

It is demonstrated that NTV-ΔF1L-C7L combines high safety with enhanced replication and immunogenicity, supporting its value as a novel vaccine vector and its potential application in controlling the current global monkeypox outbreak.

Jiao Ren, Shi-Yuan Liu, Hang Yuan et al. · 0 citations

We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.