A context-dependent defense-burden model of EV-mediated stress adaptation under combined antibiotic and metal stress is supported and EV-induced metabolic interference is highlighted as a potential therapeutic strategy against resistant pathogens in aquaculture.
Yan Yuan, Hongmin Zhang, Peng-Ju Zhao et al.· Ecotoxicology and Environmen...· 0 citations
It is demonstrated that MrFTRP1 exerts a dual-regulatory functioning as a positive regulator of conidiation and pathogenesis but a negative regulator of environmental stress tolerance, which expands the understanding of the regulatory diversity within the C6 TF family and identifies him as a promising target for the ge...
Chentian Jiang, Hao Wu, You-Gui Tong et al.· Journal of Invertebrate Path...· 0 citations
Findings underscore a significant role for VdOMO in siderophore-associated iron acquisition, fungal development, stress adaptation, and the early stages of host colonization in V. dahliae.
Yu-Sha Du, Lixinyu Sun, Kang-Wei Xie et al.· Frontiers in Plant Science· 0 citations
Comparative transcriptomic analysis revealed that BbLdh mediated numerous metabolic pathways and physiological responses to oxidative stress, deepening the understanding of metabolic pathways during fungal interaction with the hosts.
Hao Zhang, Xin-Yi Wang, Xue-Ting Wang et al.· Journal of Invertebrate Path...· 0 citations
Results indicate that VdRgt1 is an important regulator in V. dahliae, coordinating hyphal development, the timing of microsclerotia development and melanin accumulation, carbon and energy metabolism, stress adaptation, and virulence.
The findings deepen the understanding of epitranscriptomic regulation in fungal pathogenicity and represent a potential candidate for future target-based intervention strategies, pending validation through chemical or genetic approaches.