Diurnal profiles of DHEAS and cortisol/DHEAS-ratio remain equally altered in between depressive episodes, and may predict future recurrence, which suggests they represent an endophenotypic vulnerability trait rather than a state-effect, which provides a new road to understand recurrent depression and its prevention.
It is suggested that 5-HTTLPR-related differences, when present, may be more detectable in overall post-awakening cortisol output than in baseline-relative increase, which is more detectable in overall post-awakening cortisol output than in baseline-relative increase.
R. Jonassen, Ø. Øverli, E. Hilland et al.· Comprehensive Psychoneuroend...· 0 citations
OBJECTIVES
Cortisol dysregulation, reflective of hypothalamic-pituitary-adrenal (HPA) axis dysregulation, has been linked to executive functioning (EF) decline. However, substantial effect-size heterogeneity across studies highlights the potential role of psychosocial moderators. We investigated whether the severity of...
Nur Hani Hani Zainal, Stephanie Noble· The journals of gerontology....· 0 citations
Nonlinear interactions between cortisol indices and daily stressor severity appear to predict 9-year alcohol use disorder and substance use disorder severity, with cortisol area under the curve emerging as the most robust indicator.
Nur Hani Hani Zainal, Natalia Van Doren· Addiction· 0 citations
Whether pubertal timing across the ages of 8–15.5 years was associated with diurnal cortisol slope, the cortisol awakening response, total morning cortisol, and total daily cortisol output at the age of 15.5 years was sought.
Background/Objectives: Glucocorticoids have been shown to improve fear extinction learning in preclinical and human studies. We hypothesized an impact of the circadian rhythm of cortisol on exposure therapy in patients with anxiety spectrum disorders. Methods: Sixteen patients suffering from obsessive–compulsive disord...
Michael Kellner, Maja Santai Mareljic, A. Yassouridis· Journal of Clinical Medicine· 0 citations
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