Skip to content

Depression, immune-metabolic alterations and mortality in haemodialysis: a prospective cohort study

Jul 2026 · medRxiv · 0 citations
Medicine

TL;DR

Depression may identify a clinically relevant risk state among people receiving haemodialysis and require validation in larger, prospectively sampled cohorts, including potential sex differences in routine biomarkers.

View source

Similar papers

Review Aug 2026

Depressive symptom heterogeneity and mortality in a prospective U.S. cohort

Examining PHQ-9 total score, affective and somatic domains, and individual items in relation to all-cause, heart disease, and non-cardiac mortality using survey-weighted Cox models suggested symptom-level heterogeneity, but item-level modeling did not meaningfully improve discrimination.

Ze Jin · 0 citations
Review Open access Jul 2026

Immune disturbances cluster around specific depressive phenotypes under conditions of structural adversity

Higher and lower hs-CRP profiles clustered around distinct latent depressive phenotypes, supporting biologically heterogeneous depressive presentations within a socially exposed urban population.

Caio Hofmann Francisco Alves, Fausto Coutinho-Lourenço, Yuan-Pang Wang et al. · 0 citations
Open access Aug 2026

Metabolomic and Lipidomic Signatures of Depressive Symptoms in the REasons for Geographic And Racial Differences in Stroke (REGARDS) Study

Multiple lipid species, particularly phosphatidylethanolamines (PEs) and triglycerides (TGs), were significantly associated with depressive symptoms after FDR correction in longitudinal models, supporting further mechanistic and biomarker investigations.

Ç. Dağlı, N. Armstrong, P. Patel et al. · 0 citations
Review Open access Jul 2026

Sleep Duration and the Association Between Systemic Inflammatory Response Index and Depressive Symptoms Among Emerging Adults: Evidence from NHANES 2005-2023.

Higher SIRI levels were associated with increased odds of depressive symptoms among emerging adults, and sleep duration played a modest suppressor role in this relationship, suggesting complex interactions between inflammation, sleep, and mental health warranting further investigation through prospective studies.

Yingying Zhang, Yunyun Zheng, Yuting Zhang et al. · 0 citations
Open access Aug 2026

Longitudinal association between insulin resistance and depressive symptoms in older adults: the mediating role of inflammation in the ELSA cohort

The findings suggest that improvements in insulin sensitivity are associated with a lower risk of depressive symptoms in older adults and appears to be partially mediated by systemic inflammation.

Yiming Ma, Zhi-Yong Hou, Bei Yao et al. · 0 citations

We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.