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Open access Aug 2026

Infradian rhythms of human heart rate reveal distinct multiday cycle periods in healthy adults

The prevalence of infradian, or multiday heart rate rhythms in healthy young people motivates further scientific investigation to understand the mechanisms of these rhythms and their potential association with autonomic function, and risk of disease or disease-specific symptoms.

R. D. De Silva, R. Stirling, J. Naim-Feil et al. · 0 citations
Aug 2026

Multiday rhythms shape mood dynamics in depression

The results identify multidien rhythms as an organizing principle of mood in depression and a forecastable, modifiable target for chronotherapeutic neuromodulation.

N. Sekar, J.-M. Fan, K. Sellers et al. · 0 citations
Open access Aug 2026

Parsing inter-individual variability in the digital phenotype across the menstrual cycle

This work decomposes the digital phenotype dynamics into latent trajectories and uses each individual's trajectory membership as a moderator when modelling psychopathology over the same timeframe, applied in the context of mood symptom exacerbation across the menstrual cycle.

L. Knol, A. Nagpal, F. Hussain et al. · 0 citations
Aug 2026

Characterizing Nonlinear Heterogeneous Sleep Trajectories across the Menstrual Cycle in a Transdiagnostic Psychiatric Population.

Sleep trajectories across the menstrual cycle are heterogeneous and meaningfully coupled with psychiatric symptom patterns, which support cycle-aware sleep monitoring and suggest that cyclical sleep disruption may help identify windows of heightened psychiatric risk, motivating replication and personalized intervention...

A. Nagpal, Anna Patterson, Ashley Ross et al. · 0 citations
Open access Aug 2026

Autonomic and limbic system functioning, early life stress, and depressive symptoms in adolescence

Background Adolescence is a critical window for autonomic and limbic development and a period of elevated risk for depression. Although autonomic and limbic system function have, independently, been linked to depression, they are coupled and both influenced by early life stress (ELS). We do not yet know, however, wheth...

Eugenia Giampetruzzi, C. Antonacci, Jean Rachel Bahk et al. · 0 citations

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