AI Networking Cookbook: Practical recipes for AI-assisted network automation and development
TL;DR
The heterozygous TG genotype is associated with a lower BMI and a more favorable distribution of adipose tissue in obese women under 50 years of age, indicating the important role of sex hormones in mediating the effect of this polymorphism.
It was shown that the frequency of the alternative allele A of rs3828942 in Buryat adolescents is significantly higher than in the group of Russian adolescents, which is consistent with global data on a higher frequency of the allele A of rs3828942 in Asian populations.
This study is the first to demonstrate a BMI—specific correlation between GWAS-significant for estradiol levels polymorphism rs117585797 anoctamin-2 (C > A) and PE: this SNP was PE-associated in preBMI < 25 pregnant women and not linked with PE risk in preBMI ≥ 25 pregnant women.
The association of UCP1 with BMI in the subjects of this study does not agree with the conclusions found in the scientific literature about an increased risk of obesity among G* allele carriers in Caucasian samples, but the associations between UCP2-3 and lipid metabolism parameters in Ob Ugrians are consistent with th...
A possible role for the rs7903146 polymorphism of the TCF7L2 gene, in the risk of primary KOA and obesity is suggested.
OLR1 rs11053646 SNP does not appear to be associated with T2D risk in Saudi adults, and small sample size may have limited statistical power to detect potential associations.
The findings suggest that genotype-informed dietary strategies may need to be sex-specific, and that the window for intervention may be earlier in life than currently practised.
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