Association of Fibrinogen Beta Chain (FGB) rs1800790 and ITGB3 rs5918 gene variants with coagulation and ınflammation parameters according to sex in COVID-19 patients.
Jul 2026· Journal of Thrombosis and Thrombolysis· 0 citations· 23 references
Medicine
TL;DR
The combined influence of sex and coagulation-related genetic variants on thrombo-inflammatory patterns in COVID-19 patients highlights the potential clinical importance of considering sex-genotype interactions when evaluating thrombo-inflammatory responses and may contribute to more personalized risk assessment and management strategies in patients with COVID-19.
The PROC rs146922325 variant was associated with an increased risk of venous thrombosis in the Taiwanese population and the potential value of genetic risk stratification in thrombosis research is supported.
Chi-Yen Chen, I-Chieh Chen, Guan-Cheng Lin et al.· Blood Research· 0 citations
In patients with COVID-19-DAD and T2D, the presence of the mutant allele Т of the ITGA2 gene rs1126643 polymorphism and allele С of the ITGB3 gene rs5918 polymorphism increases the rate of the collagen- and ADP-induced platelet aggregation.
M. Osikov, V. Antonov, S. Zotov· Bulletin of Russian State Me...· 0 citations
Haplotype Arg16ArgGln27Gln of β2-AR gene is a predictor of LC development, increasing the risk of disease development 2,4 times and is associated with LC severity according to Child-Pugh classification.
A. V. Molchanova, E. I. Mikhailova, A. Kalinin et al.· Experimental and Clinical Ga...· 0 citations
This study is the first to demonstrate that the TGFA rs3732248 polymorphism is significantly associated with PCOS susceptibility in an Iranian population, providing novel genetic evidence supporting a role for TGFA in PCOS pathogenesis and warrant replication in larger independent cohorts.
F. Keykha, M. Mohammadi, Marzieh Ghasemi et al.· BMC Women's Health· 0 citations
BAFF polymorphisms are significantly associated with PE susceptibility in the Iranian population and may serve as potential biomarkers for PE risk assessment.
Kosar Shirvani Baghbabouie, D. Jahantigh, F. Forghani et al.· Personalized Medicine· 0 citations
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