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Case report Open access

Chronic Venous Intervention Using a Large-Bore, Vacuum-Assisted Aspiration System

Jul 2026 · JACC Case Reports · Vol 31, pp. 109135 · 0 citations · 5 references
Medicine

TL;DR

The patient had a history of implantable cardioverter-defibrillator insertion, who presented for chronic pulmonary embolism, and was later diagnosed with an implantable cardioverter-defibrillator infection, complicated with septic pulmonary embolization.

Abstract

Background Chronic venous thromboembolism can affect various vascular beds and is often treated medically. Although endovascular intervention is an option, it is challenging with currently available equipment and revascularization techniques. Case Summary Patient 1 presented with superior vena cava obstruction due to a thrombosed superior vena cava graft after thymectomy. Successful revascularization was achieved using both the Symphony aspiration catheter (Imperative Care) and the ClotTriever catheter (Inari), with placement of an additional covered stent. There was immediate resolution of symptoms. Patient 2 had a history of implantable cardioverter-defibrillator insertion, who presented for chronic pulmonary embolism. Symphony catheter aspiration yielded both chronic thrombus and organized tissue. She was later diagnosed with an implantable cardioverter-defibrillator infection, complicated with septic pulmonary embolization. She was further managed with lead extraction, percutaneous vegetation aspiration and antibiotics. Take-Home Message With newer generation devices, chronic venous intervention is becoming more feasible and could potentially be offered to more patients who fail medical therapy.

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