Skip to content
Open access

Bidirectional Mamba and routing-attention synergistic network for efficient medical image segmentation

Jul 2026 · PeerJ Computer Science · Vol 12, pp. e3941 · 0 citations · 56 references

TL;DR

A heterogeneous U-shaped architecture that strategically deploys specialized mechanisms based on component-specific functional requirements to optimize multi-scale feature integration and introduces Spatial-Channel Synergistic Attention in skip connections.

Abstract

Based on U-shaped architecture for medical image segmentation faces three fundamental challenges limiting clinical deployment: (1) architectural homogeneity problems where uniform mechanism deployment overlooks distinct encoder-decoder requirements, (2) skip connection feature fusion limitations with insufficient spatial-channel attention integration, and (3) computational efficiency vs . performance trade-offs. We propose a heterogeneous U-shaped architecture that strategically deploys specialized mechanisms based on component-specific functional requirements. Our approach utilizes Vision Mamba with Non-causal State Space Duality (VSSD) in encoder/bottleneck for efficient global context extraction, Bi-Level Routing Attention (BRA) in decoder for adaptive detail recovery, and introduces Spatial-Channel Synergistic Attention (SCSA) in skip connections to optimize multi-scale feature integration with only 0.01M additional parameters. Extensive experiments across four diverse datasets demonstrate exceptional performance: for example on Synapse dataset, our model achieves 84% Dice Similarity Coefficient and 13.76 mm Hausdorff Distance with only 23.43M parameters. Details are available on https://github.com/Yuyan-Bin/Synergistic-Network .

Read PDF

Similar papers

Open access Jul 2026

Uncertainty-guided mamba network for efficient medical image segmentation with evidential deep learning.

This work proposes an uncertainty-aware efficient segmentation framework synergizing Mamba state-space models with evidential deep learning, employing a 2D-adapted selective state-space mechanism to capture long-range dependencies with linear complexity O(L), overcoming transformers' quadratic scaling.

Siqin Sun, Chihui Long, Xingbo Dong et al. · 0 citations
Conference Sep 2026

TvaraNet: A Lightweight Mamba Neural Network for Real-Time Medical Image Segmentation

TvaraNet is pro-posed, an extremely lightweight segmentation network designed to preserve boundary fidelity under strict efficiency constraints and achieves competitive or superior boundary-aware performance compared to heavier architectures.

Sridhatta Jayaram Aithal, Vandana Bharti · 0 citations
Jul 2026

Fourier fusion and dual-path attention enhancement network for medical image segmentation

FFDA-Net introduces a Fourier feature fusion module, which selectively retains relevant features in the skip connections while suppressing irrelevant ones, thereby alleviating the issue of information interference caused by semantic differences when fusing features at different resolutions.

Le Zou, Xiangxu Bu, Zhi-Ze Wu et al. · 0 citations
Open access Aug 2026

TSPFusion: Tri-stream and prototype network for learning detail-semantic fusion in medical image segmentation

A tri-stream interaction paradigm replacing symmetric skip connections with directional fusion among semantic, spatial, and decoder-propagated streams at each decoding stage, and a Global Prototype Bank that captures dataset-level anatomical regularities via attention-based retrieval and gated EMA updates, providing pe...

Mohammed A. M. Elhassan, Qian-Fa Yuan, Zhizhong Xu et al. · 0 citations
Conference Jul 2026

ADSAM-Net: A Dual-Stage Attention Enhanced Mamba Network for 3D Medical Image Segmentation

Accurate 3D medical image segmentation is crucial for clinical use. CNNs and transformers have limitations: limited receptive fields or quadratic complexity. State space models like Mamba offer linear complexity with global perception, but existing methods (e.g., EM-Net) struggle with small organs due to poor spatial d...

Yifei Zhang, Jia-Mi Yang, Guan-Yu Lu et al. · 0 citations

We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.